2025/3/31(一)演講公告

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上層分類：系所公告

分類：演講

建立於 2025-03-24, 週一 14:58

最近更新於 2025-03-31, 週一 13:57

發佈於：2025-03-24, 週一 15:05

點擊數：1123

演講者：Professor Toshiya Sakata

演講題目：Biosensing technology based on solution-gated field-effect transistor

演講地點：博雅館102室

演講時間：114.03.31上午10點20分~12點10分

演講摘要：

In this talk, recent works on biologically coupled gate field-effect transistor (bio-FET) sensors are introduced and compared to provide a perspective. Most biological phenomena are closely related to behaviors of ions and biomolecules. This is why biosensing devices for detecting ionic and biomolecular charges contribute to the direct analysis of biological phenomena in a label-free and enzyme-free manner. Potentiometric biosensors such as bio-FET sensors, which allow the direct detection of these charges on the basis of the field effect, meet this requirement and have been developed as simple devices for in vitro diagnostics (IVD). A variety of biological ionic behaviors generated by biomolecular recognition events and cellular activities are being targeted for clinical diagnostics as well as the study of neuroscience using the bio-FET sensors. To realize these applications, bioelectrical interfaces should be formed between the electrolyte solution and the gate electrode by modifying artificially synthesized and biomimetic membranes, resulting in the selective detection of targets based on intrinsic molecular charges. Various types of semiconducting materials, not only inorganic semiconductors but also organic semiconductors, can be selected for use in bio-FET sensors, depending on the application field. In addition, a semiconductor integrated circuit device is ideal for the massively parallel detection of multiple samples. Thus, platforms based on bio-FET sensors are suitable for use in simple and miniaturized electrical circuit systems for IVD to enable the prevention and early detection of diseases.

關於講者：

服務單位：The University of Tokyo

職稱：Associate Professor

學經歷：

EDUCATION
1998.3 BS, Department of Materials Science and Engineering, Osaka University
2000.3 MS, Department of Materials Science and Engineering, Osaka University
2003.3 Ph.D., Department of Materials Science and Engineering (DC1), Osaka University
RESEARCH EXPERIENCE
2003.4 Researcher, National Institute for Materials Science (NIMS)
2006.9 Project Lecturer, Center for NanoBio Integration (Department of Materials Engineering), The University of Tokyo
2008.4 Lecturer, Department of Materials Engineering, The University of Tokyo
2011.4~ Associate Professor, Department of Materials Engineering, The University of Tokyo
(2015.3~ Outside Director　@PROVIGATE Inc.; 2015.10-2016.9 Visiting Associate Professor　@Harvard Medical School)

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