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5/6 Seminar Speech

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Speaker: Dr. Shu-Yi Lin

Topic: Caged Noble-metal Nanoclusters for Translational Medicine

SpeakerDr. Shu-Yi Lin

OrganizationNational Health Research Institutes / Institute of Biomedical Engineering and Nanomedicine

TopicCaged Noble-metal Nanoclusters for Translational Medicine

Date10:20 , 2019.5.6

LocationRoom 203, College of Engineering

Education

National Tsing Hua University / Department of Chemistry / Ph.D.

National Chung Hsing University / Department of Chemistry / MS

National Chung Hsing University / Department of Chemistry / BS

Work Experience

National Health Research Institutes / Institute of Biomedical Engineering and Nanomedicine / Investigator

National Health Research Institutes / Institute of Biomedical Engineering and Nanomedicine / Associate Investigator

National Health Research Institutes / Center for Nanomedicine Research / Assistant Investigator

Abstract

Noble-metal nanodots, or nanoclusters, which comprise several or tens of atoms and are typically smaller than 2 nm in diameter, have attracted considerable attention for their potential utility in interdisciplinary applications such as biological trackers, photosynthetic catalysts, and optical sensors. In my lab, we have successfully developed gold and platinum nanoclusters to perform in nanomedicine applications, including anti-sepsis and cancer killers. But why were gold and platinum chosen? The former was selected because the Compendium of Materia Medica notes that gold can be eaten, and this made me wonder if our ancestors had already learned of some special health benefits that gold offers. As for platinum, it was selected because cisplatin is currently the only anticancer drug on the market that contains platinum, and I wanted to know if platinum itself could be used as a drug, as this would help address the shortcomings of cisplatin (i.e. systemic toxicity and drug resistance).

20190506